Smart AI-Driven Imaging Meets High-Speed Confocal Microscopy
- Date: Thursday, 08 October 2026
- Time: 10:30 am – 5:30 pm CEST (Rome Time)
- Location: CrestOptics HQ, Via di Torre Rossa 66, 00165 Rome, Italy
Register for the event and join us at CrestOptics HQ, or access the live stream on the day (morning talk sessions only).
INTRODUCTION
We are pleased to invite you to the CrestOptics & Nikon Italy Open Day 2026, taking place on October 8th, where we will showcase the latest advancements in high-performance imaging technologies and the seamless integration between CrestOptics systems and Nikon microscopy platforms.
The event will focus on expert presentations from Nikon and CrestOptics, followed by interactive hands-on workshops.
In particular, this Open Day will feature live demonstrations of:
1) Nikon ECLIPSE Ji with the CrestOptics X-Light V3 spinning disk confocal.
Designed for both advanced live-cell imaging and routine laboratory workflows, the ECLIPSE Ji combines Nikon’s renowned optics with AI-driven automation via the NIS-Elements interface.
Trained neural networks handle alignment, focus, and acquisition parameters autonomously, minimizing user error and rapidly delivering reliable metrics like EC/IC50 values and Z-factors. As a state-of-the-art spinning disk confocal system, the CrestOptics X-Light V3 equips the ECLIPSE Ji with high-speed optical sectioning and exceptional resolution, making it ideal for capturing fast biological dynamics and exploring complex 3D microenvironments without complex manual setups.
Nikon ECLIPSE Ji + CrestOptics X-Light V3
Nikon ECLIPSE Ji integrated with CrestOptics X-Light V3 spinning disk confocal. (Left) The automated Nikon ECLIPSE Ji benchtop system equipped with the CrestOptics X-Light V3 spinning disk confocal unit. (Right) 3D confocal acquisition of a biological spheroid nuclei signal, followed by 3D segmentation of individual cellular nuclei within the spheroid volume using NIS-Elements Software.
2) Nikon Ti2-E body integrated with both the X-Light V3 spinning disk confocal and the DeepSIM X-Light super-resolution module.
This multimodal combined solution bridges wide-context imaging with nanoscale precision on a single setup. It allows researchers to seamlessly switch from large field-of-view overviews (such as full 3D tissue architectures or broad cell populations) to ultra-sharp sub-diffraction detail (like neuronal networks or chromosome segregation dynamics) on the exact same region, preserving sample integrity while maximizing data completeness.
Nikon Ti2-E body integrated with both the X-Light V3 spinning disk confocal and the DeepSIM X-Light super-resolution module. (Left) Nikon ECLIPSE Ti2-E inverted microscope integrated with both CrestOptics X-Light V3 spinning disk confocal and DeepSIM super-resolution modules. (Middle) Stitched, large field-of-view 3D confocal volume of a mouse cerebellum section mapping the overall tissue architecture. Scale bar: 500 µm. (Right) Super-resolution zoom-in on the exact same region, revealing fine subcellular details and the ultra-sharp organization of myelin sheaths and neurons. Scale bar: 20 µm.
The event will focus on expert presentations from Nikon and CrestOptics, followed by interactive hands-on workshops.
In particular, this Open Day will feature live demonstrations of:
1) Nikon ECLIPSE Ji with the CrestOptics X-Light V3 spinning disk confocal.
Designed for both advanced live-cell imaging and routine laboratory workflows, the ECLIPSE Ji combines Nikon’s renowned optics with AI-driven automation via the NIS-Elements interface. Trained neural networks handle alignment, focus, and acquisition parameters autonomously, minimizing user error and rapidly delivering reliable metrics like EC/IC50 values and Z-factors. As a state-of-the-art spinning disk confocal system, the CrestOptics X-Light V3 equips the ECLIPSE Ji with high-speed optical sectioning and exceptional resolution, making it ideal for capturing fast biological dynamics and exploring complex 3D microenvironments without complex manual setups.
Nikon ECLIPSE Ji integrated with CrestOptics X-Light V3 spinning disk confocal. (Left) The automated Nikon ECLIPSE Ji benchtop system equipped with the CrestOptics X-Light V3 spinning disk confocal unit. (Right) 3D confocal acquisition of a biological spheroid nuclei signal, followed by 3D segmentation of individual cellular nuclei within the spheroid volume using NIS-Elements Software.
2) Nikon Ti2-E body integrated with both the X-Light V3 spinning disk confocal and the DeepSIM X-Light super-resolution module.
This multimodal combined solution bridges wide-context imaging with nanoscale precision on a single setup. It allows researchers to seamlessly switch from large field-of-view overviews (such as full 3D tissue architectures or broad cell populations) to ultra-sharp sub-diffraction detail (like neuronal networks or chromosome segregation dynamics) on the exact same region, preserving sample integrity while maximizing data completeness.
Nikon Ti2-E body integrated with both the X-Light V3 spinning disk confocal and the DeepSIM X-Light super-resolution module. (Left) Nikon ECLIPSE Ti2-E inverted microscope integrated with both CrestOptics X-Light V3 spinning disk confocal and DeepSIM super-resolution modules. (Middle) Stitched, large field-of-view 3D confocal volume of a mouse cerebellum section mapping the overall tissue architecture. Scale bar: 500 µm. (Right) Super-resolution zoom-in on the exact same region, revealing fine subcellular details and the ultra-sharp organization of myelin sheaths and neurons. Scale bar: 20 µm.
AGENDA
- 10:30 – 11:30 | Welcome & Coffee Break
- 11:30 – 12:15 | Introduction to Nikon ECLIPSE Ji |Speaker: Matteo Parri (Nikon Italy, Branch of Nikon Europe B.V.)
- 12:15 – 13:00 | Introduction to CrestOptics X-Light V3 Spinning Disk | Speaker: Francesco Bacchi (CrestOptics)
- 13:00 – 13:30 | Lunch Break (Sponsored by Nikon & CrestOptics)
- 13:30 – 17:30 | HANDS-ON SESSIONS – PRACTICAL DEMONSTRATIONS
USEFUL INFORMATION – The afternoon hands-on sessions will run in parallel across the specialized imaging systems described above:
- Nikon ECLIPSE Ji with the CrestOptics X-Light V3 spinning disk confocal.
- Nikon Ti2-E body integrated with both the X-Light V3 spinning disk confocal and the DeepSIM X-Light super-resolution module.
HANDS-ON TIMETABLE
- 13:30 – 14:30 | Demo Session 1
- 14:30 – 15:30 | Demo Session 2
- 15:30 – 16:30 | Demo Session 3
- 16:30 – 17:30 | Demo Session 4
CrestOptics & Nikon Italy: Strengthening a Long-Lasting Partnership
For over a decade, Nikon Italy, Branch of Nikon Europe B.V and CrestOptics have maintained a strong strategic partnership focused on advancing imaging technologies. By combining high-end hardware with seamless software integration, our microscopy ecosystem empowers researchers across academia and industry with lightning-fast, high-resolution cellular imaging, driving discoveries from basic science to clinical diagnostics.
